DDX41-related myeloid neoplasia

MYELOID NEOPLASIA Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies

1Department of Translational Hematology and Oncology Research, 2Department of Hematologic Oncology and Blood Disorders, Taussig Cancer Institute Center, and 3Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH; 4Laboratory Medicine, Ewha Womans University, School of Medicine, Seoul, South Korea; 5Department of Haematological Medicine, King’s College London School of Medi...

Two novel germline DDX41 mutations in a family with inherited myelodysplasia/acute myeloid leukemia.

The Danish National Chronic Myeloid Neoplasia Registry

AIM The Danish National Chronic Myeloid Neoplasia Registry (DCMR) is a population-based clinical quality database, introduced to evaluate diagnosis and treatment of patients with chronic myeloid malignancies. The aim is to monitor the clinical quality at the national, regional, and hospital departmental levels and serve as a platform for research. STUDY POPULATION The DCMR has nationwide cove...

MYELOID NEOPLASIA Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia

1Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD; 2Laboratory of Molecular Oncology, Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Slovakia; 3Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC; and 4Centre for Biologics Research,...

Therapy-related myeloid leukemia following Pleuropulmonary blastoma: A case report

The development of secondary malignancy (SM) is the most worrisome long-term complication of childhood cancer. Acute myeloid leukemia is the most prevalent neoplasm that occurs after treatment with alkylating agents and topoisomerase II inhibitors. Pleuropulmonary blastoma (PPB) is a rare lung neoplasm in children. Type II and type III of this cancer are markedly aggressive and have a recurrent...